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federal_register: E7-1528

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document_number title type abstract publication_date pub_year pub_month html_url pdf_url agency_names agency_ids excerpts
E7-1528 Viruses, Serums, Toxins, and Analogous Products; Detection of Avian Lymphoid Leukosis Virus Proposed Rule We are proposing to amend the Virus-Serum-Toxin Act regulations concerning testing for avian lymphoid leukosis in veterinary biologics to specify that the test is for the detection of extraneous replicating avian leukosis virus; require such testing to be conducted using a procedure that will detect extraneous replicating avian leukosis virus and that is acceptable to the Animal and Plant Health Inspection Service; require firms to develop a procedure to test for lymphoid leukosis virus contamination in the case of vaccine virus cytopathic to chick embryo cell cultures; and specify the equivalent inoculum dose of vaccine to be used when testing certain specified chicken vaccines for lymphoid leukosis virus. These proposed changes would update the testing for lymphoid leukosis virus contamination by prescribing a test procedure that increases the probability of detecting atypical lymphoid leukosis viruses such as those recently found in a contaminated vaccine. 2007-01-31 2007 1 https://www.federalregister.gov/documents/2007/01/31/E7-1528/viruses-serums-toxins-and-analogous-products-detection-of-avian-lymphoid-leukosis-virus https://www.govinfo.gov/content/pkg/FR-2007-01-31/pdf/E7-1528.pdf Agriculture Department; Animal and Plant Health Inspection Service 12,22 We are proposing to amend the Virus-Serum-Toxin Act regulations concerning testing for avian lymphoid leukosis in veterinary biologics to specify that the test is for the detection of extraneous replicating avian leukosis virus; require such testing to...

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