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federal_register: 2023-28596

All Federal Register documents (rules, proposed rules, notices, presidential documents) from 1994 to present.

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document_number title type abstract publication_date pub_year pub_month html_url pdf_url agency_names agency_ids excerpts
2023-28596 Potency Assurance for Cellular and Gene Therapy Products; Draft Guidance for Industry; Availability Notice The Food and Drug Administration (FDA, Agency, or we) is announcing the availability of a draft guidance entitled "Potency Assurance for Cellular and Gene Therapy Products." FDA is issuing this draft guidance to provide recommendations to help assure the potency of human cellular therapy or gene therapy (CGT) products at all stages of the product lifecycle. FDA is recommending a comprehensive approach to potency assurance of CGT products that is grounded in quality risk management. For investigational products, we describe how to progressively implement a strategy for potency assurance during product development and provide additional considerations to help assure the potency of products that are undergoing rapid clinical development. For licensed products, we describe requirements for potency assurance, including testing required for lot release. 2023-12-28 2023 12 https://www.federalregister.gov/documents/2023/12/28/2023-28596/potency-assurance-for-cellular-and-gene-therapy-products-draft-guidance-for-industry-availability https://www.govinfo.gov/content/pkg/FR-2023-12-28/pdf/2023-28596.pdf Health and Human Services Department; Food and Drug Administration 221,199 The Food and Drug Administration (FDA, Agency, or we) is announcing the availability of a draft guidance entitled "Potency Assurance for Cellular and Gene Therapy Products." FDA is issuing this draft guidance to provide recommendations to help assure...

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