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federal_register: 2021-27812

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document_number title type abstract publication_date pub_year pub_month html_url pdf_url agency_names agency_ids excerpts
2021-27812 Assessing the Credibility of Computational Modeling and Simulation in Medical Device Submissions; Draft Guidance for Industry and Food and Drug Administration Staff; Availability Notice The Food and Drug Administration (FDA or Agency) is announcing the availability of the draft guidance entitled "Assessing the Credibility of Computational Modeling and Simulation in Medical Device Submissions." Computational modeling and simulation (CM&S) can be used in a variety of ways in medical device applications, including to perform "in silico" device testing or as part of software embedded in a device. This guidance provides a risk-based framework that can be used in the credibility assessment of computational modeling and simulation (CM&S) used in medical device regulatory submissions. The draft guidance is intended to improve the consistency and transparency of the review of computational modeling evidence. This draft guidance is not final nor is it in effect at this time. 2021-12-23 2021 12 https://www.federalregister.gov/documents/2021/12/23/2021-27812/assessing-the-credibility-of-computational-modeling-and-simulation-in-medical-device-submissions https://www.govinfo.gov/content/pkg/FR-2021-12-23/pdf/2021-27812.pdf Health and Human Services Department; Food and Drug Administration 221,199 The Food and Drug Administration (FDA or Agency) is announcing the availability of the draft guidance entitled "Assessing the Credibility of Computational Modeling and Simulation in Medical Device Submissions." Computational modeling and simulation...

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