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federal_register: 2018-26957

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2018-26957 Data Integrity and Compliance With Drug CGMP: Questions and Answers; Guidance for Industry; Availability Notice The Food and Drug Administration (FDA or Agency) is announcing the availability of a final guidance for industry entitled "Data Integrity and Compliance With Drug CGMP: Questions and Answers." The purpose of the guidance is to clarify the role of data integrity in current good manufacturing practice (CGMP) for drugs. (Unless otherwise noted, the term CGMP refers to CGMPs for drugs, including biologics.) The guidance has been developed in response to an increase in findings of data integrity lapses in recent inspections. FDA expects that all data be reliable and accurate. CGMP regulations and guidance allow for flexible and risk-based strategies to prevent and detect data integrity issues. Firms should implement meaningful and effective strategies to manage their data integrity risks based on their process understanding and knowledge management of technologies and business models. 2018-12-13 2018 12 https://www.federalregister.gov/documents/2018/12/13/2018-26957/data-integrity-and-compliance-with-drug-cgmp-questions-and-answers-guidance-for-industry https://www.govinfo.gov/content/pkg/FR-2018-12-13/pdf/2018-26957.pdf Health and Human Services Department; Food and Drug Administration 221,199 The Food and Drug Administration (FDA or Agency) is announcing the availability of a final guidance for industry entitled "Data Integrity and Compliance With Drug CGMP: Questions and Answers." The purpose of the guidance is to clarify the role of data...

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