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federal_register: 2012-29461

All Federal Register documents (rules, proposed rules, notices, presidential documents) from 1994 to present.

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document_number title type abstract publication_date pub_year pub_month html_url pdf_url agency_names agency_ids excerpts
2012-29461 Guidance for Industry on Limiting the Use of Certain Phthalates as Excipients in Center for Drug Evaluation and Research-Regulated Products; Availability Notice The Food and Drug Administration (FDA) is announcing the availability of a guidance for industry entitled "Limiting the Use of Certain Phthalates as Excipients in CDER-Regulated Products." This guidance provides the pharmaceutical industry with the Center for Drug Evaluation and Research's (CDER's) current thinking on the potential human health risks associated with exposure to dibutyl phthalate (DBP) and di(2-ethylhexyl) phthalate (DEHP). In particular, the guidance recommends that the pharmaceutical industry avoid the use of these two specific phthalates as excipients in CDER-regulated drug and biologic products, including prescription and nonprescription products. 2012-12-06 2012 12 https://www.federalregister.gov/documents/2012/12/06/2012-29461/guidance-for-industry-on-limiting-the-use-of-certain-phthalates-as-excipients-in-center-for-drug https://www.govinfo.gov/content/pkg/FR-2012-12-06/pdf/2012-29461.pdf Health and Human Services Department; Food and Drug Administration 221,199 The Food and Drug Administration (FDA) is announcing the availability of a guidance for industry entitled "Limiting the Use of Certain Phthalates as Excipients in CDER-Regulated Products." This guidance provides the pharmaceutical industry with the...

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