id,agency_id,docket_id,title,document_type,subtype,posted_date,posted_year,posted_month,comment_start_date,comment_end_date,last_modified,fr_doc_num,open_for_comment,withdrawn,object_id
EPA-HQ-OAR-2004-0074-0221,EPA,EPA-HQ-OAR-2004-0074,Afton Chemical Corporation letter describing proposed continuation of the Alternative Tier 2 reporting procedure to include development of the Mn PBPK models for humans,Supporting & Related Material,"Letter, Memorandum, Email",2009-08-19T04:00:00Z,2009,8,,,2009-08-19T17:38:56Z,,0,0,0900006480a0d174
EPA-HQ-OAR-2004-0074-0220,EPA,EPA-HQ-OAR-2004-0074,Model Code for the Manganese Physiologically-Based Pharmcokinetic Gestation and Lactation Rat Model,Supporting & Related Material,Data,2009-06-23T04:00:00Z,2009,6,,,2009-06-23T14:13:08Z,,0,0,09000064809d2e22
EPA-HQ-OAR-2004-0074-0219,EPA,EPA-HQ-OAR-2004-0074,EPA Memorandum Transmiting Comments on Review and Approval of the Manganese Physiologically-Based Pharmacokinetic Gestation and Lactation Rat Model,Supporting & Related Material,"Letter, Memorandum, Email",2009-06-19T04:00:00Z,2009,6,,,2009-06-19T20:00:05Z,,0,0,09000064809d2e23
EPA-HQ-OAR-2004-0074-0215,EPA,EPA-HQ-OAR-2004-0074,"Email from Dr. Jerry Roper, Afton Chemical, providing response to EPA's December 23, 2008 Comments on Manganese pharmacokinetic (PBPK) Gestation and Lactation Rat Model",Supporting & Related Material,"Letter, Memorandum, Email",2009-06-19T04:00:00Z,2009,6,,,2009-06-19T19:42:45Z,,0,0,09000064809d27c5
EPA-HQ-OAR-2004-0074-0216,EPA,EPA-HQ-OAR-2004-0074,"Afton Manuscript to be Submitted for Publication, Entitled, ""Evaluating Placental Transfer and Tissue Concentrations of Manganese in the Pregnant Rat and Fetuses after Inhaltion Exposures with a PBPK Model",Supporting & Related Material,Publication - Copyrighted Materials,2009-06-19T04:00:00Z,2009,6,,,2011-10-26T16:58:20Z,,0,0,09000064809d27c6
EPA-HQ-OAR-2004-0074-0217,EPA,EPA-HQ-OAR-2004-0074,"Afton Manuscript That Has Been Accepted for Publicaiton Entitled, ""Lactational Transfer of Manganese in Rats: Predicting Manganese Tissue Concentration in the Dam and Pups from Inhalation Exposure with a Pharmacokinetic Model",Supporting & Related Material,Publication - Copyrighted Materials,2009-06-19T04:00:00Z,2009,6,,,2011-10-26T17:04:17Z,,0,0,09000064809d2e1e
EPA-HQ-OAR-2004-0074-0218,EPA,EPA-HQ-OAR-2004-0074,"Afton Report by Drs. Anderson and Yoon Entitled, Documentation of the Physiologically Based Pharmacokinetic Model for Manganese During Gestation and Lactation in the Rat (3/31/08)",Supporting & Related Material,Report,2009-06-19T04:00:00Z,2009,6,,,2009-06-19T19:53:01Z,,0,0,09000064809d2e21
EPA-HQ-OAR-2004-0074-0213,EPA,EPA-HQ-OAR-2004-0074,Agenda for 1/29/09 Meeting on Mn PBPK Models (Physiologically Based Pharmacokinetic/ Pharmacodynamic (PBPK/PD) Model),Supporting & Related Material,Meeting/Teleconference Materials,2009-02-09T05:00:00Z,2009,2,,,2009-02-09T13:06:54Z,,0,0,090000648084634c
EPA-HQ-OAR-2004-0074-0214,EPA,EPA-HQ-OAR-2004-0074,Presentation by Dr. Jerry Roper at 1/29/09 Meeting,Supporting & Related Material,Meeting/Teleconference Materials,2009-02-09T05:00:00Z,2009,2,,,2009-02-09T13:07:01Z,,0,0,0900006480846364
EPA-HQ-OAR-2004-0074-0212,EPA,EPA-HQ-OAR-2004-0074,Presentation by Dr. Harvey Clewell at the 1/29/09 meeting,Supporting & Related Material,Meeting/Teleconference Materials,2009-02-05T05:00:00Z,2009,2,,,2009-02-05T15:01:06Z,,0,0,09000064808463cf
EPA-HQ-OAR-2004-0074-0211,EPA,EPA-HQ-OAR-2004-0074,Presentation by Dr. Miyoung Yoon at 1/29/09 meeting,Supporting & Related Material,Meeting/Teleconference Materials,2009-02-05T05:00:00Z,2009,2,,,2009-02-05T15:01:00Z,,0,0,09000064808463c2
EPA-HQ-OAR-2004-0074-0210,EPA,EPA-HQ-OAR-2004-0074,Presentation by Dr. Andy Nong at 1/29/09 meeting,Supporting & Related Material,Meeting/Teleconference Materials,2009-02-05T05:00:00Z,2009,2,,,2009-02-05T15:00:56Z,,0,0,09000064808463ae
EPA-HQ-OAR-2004-0074-0209,EPA,EPA-HQ-OAR-2004-0074,Presentation by Dr. Melvin Andersen during 1/29/09 meeting,Supporting & Related Material,Meeting/Teleconference Materials,2009-02-05T05:00:00Z,2009,2,,,2009-02-05T15:00:51Z,,0,0,0900006480846393
EPA-HQ-OAR-2004-0074-0208,EPA,EPA-HQ-OAR-2004-0074,Bibliography of Scientific Papers Published From the MMT Alternative Tier 2 (Stage 1) Test Program,Supporting & Related Material,,2009-02-05T05:00:00Z,2009,2,,,2009-02-05T15:00:46Z,,0,0,090000648084637f
EPA-HQ-OAR-2004-0074-0197,EPA,EPA-HQ-OAR-2004-0074,Afton Transmittal Letter for Developmental Mn Physiologically-Based Pharmacokinetic (PBPK) Models (29 August 2008),Supporting & Related Material,"Letter, Memorandum, Email",2009-01-16T05:00:00Z,2009,1,,,2009-01-16T18:06:49Z,,0,0,09000064808210ec
EPA-HQ-OAR-2004-0074-0204,EPA,EPA-HQ-OAR-2004-0074,USEPA Comments and Approval of Manganese (Mn) Pharmacokinetic (PBPK) Non-Human Primate Model,Supporting & Related Material,"Letter, Memorandum, Email",2009-01-16T05:00:00Z,2009,1,,,2009-01-16T18:07:19Z,,0,0,09000064808214d2
EPA-HQ-OAR-2004-0074-0205,EPA,EPA-HQ-OAR-2004-0074,USEPA Comments on Manganese (Mn) Physiologically Based Pharmacokinetic Modeling (PBPK) Gestation and Lactation Rat Model,Supporting & Related Material,"Letter, Memorandum, Email",2009-01-16T05:00:00Z,2009,1,,,2009-01-16T19:21:07Z,,0,0,09000064808213b7
EPA-HQ-OAR-2004-0074-0206,EPA,EPA-HQ-OAR-2004-0074,Afton Transmittal Letter Providing Additional Documentation on the Physiologically-Based Pharmacokinetic (PBPK) Model for Manganese in Non-Human Primates,Supporting & Related Material,"Letter, Memorandum, Email",2009-01-16T05:00:00Z,2009,1,,,2009-01-16T19:21:11Z,,0,0,09000064808213f6
EPA-HQ-OAR-2004-0074-0207,EPA,EPA-HQ-OAR-2004-0074,A Revised Manuscript on Manganese Physiologically-based Pharmacokinetic (PBPK) Model for Non-human Primates,Supporting & Related Material,Publication - Copyrighted Materials,2009-01-16T05:00:00Z,2009,1,,,2011-10-26T16:53:42Z,,0,0,090000648082142d
EPA-HQ-OAR-2004-0074-0201,EPA,EPA-HQ-OAR-2004-0074,Files Containing Modeling Code for Manganese (Mn) Developmental Models,Supporting & Related Material,Data,2009-01-16T05:00:00Z,2009,1,,,2009-01-16T18:07:07Z,,0,0,0900006480821318
EPA-HQ-OAR-2004-0074-0199,EPA,EPA-HQ-OAR-2004-0074,A Hamner Institute Presentation entitled: Manganese Developmental Model for Rats,Supporting & Related Material,Study,2009-01-16T05:00:00Z,2009,1,,,2009-01-16T18:07:00Z,,0,0,09000064808211cd
EPA-HQ-OAR-2004-0074-0200,EPA,EPA-HQ-OAR-2004-0074,Technical Advisory Panel (TAP) Comments on the Developmental Models and Dr. Andersen's Response,Supporting & Related Material,Report,2009-01-16T05:00:00Z,2009,1,,,2009-01-16T18:07:04Z,,0,0,09000064808212c2
EPA-HQ-OAR-2004-0074-0198,EPA,EPA-HQ-OAR-2004-0074,Manganese Developmental Physiologically-Based Pharmacokinetic (PBPK) Model Report,Supporting & Related Material,Report,2009-01-16T05:00:00Z,2009,1,,,2009-01-16T18:06:53Z,,0,0,0900006480821117
EPA-HQ-OAR-2004-0074-0202,EPA,EPA-HQ-OAR-2004-0074,"Afton Report addressing EPA's May 11, 2001 comments on manganese (Mn) Pharmacokinetic (PBPK) Non-human primate model (27 October 2008)",Supporting & Related Material,Report,2009-01-16T05:00:00Z,2009,1,,,2009-01-16T18:07:11Z,,0,0,0900006480821456
EPA-HQ-OAR-2004-0074-0203,EPA,EPA-HQ-OAR-2004-0074,Model Code for the Manganese (Mn) Pharmacokinetic (PBPK) Non-Human Primate Model,Supporting & Related Material,Physical Item,2009-01-16T05:00:00Z,2009,1,,,2009-01-16T18:07:15Z,,0,0,09000064808214a1